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microsatellite instability analysis  (Takeda)

 
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    Takeda microsatellite instability analysis
    Microsatellite Instability Analysis, supplied by Takeda, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/microsatellite+instability+analysis/pm40526642-839-35-12?v=Takeda
    Average 90 stars, based on 1 article reviews
    microsatellite instability analysis - by Bioz Stars, 2026-07
    90/100 stars

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    Vδ chain usage in tumour-infiltrating γδ T cells. Single cell suspensions were isolated from frozen tumour specimens and the CDR3 region analysed with ultra-sensitive sequencing using unique molecular identifiers. A The number of clones in the ten most frequent clonotypes from each patient. Colour coding shows the Vδ usage in the respective clonotypes. B Chord diagram showing the distribution of clones using the different Vδ chains in individual patients. C Gini-Simpson index of diversity was calculated for each tumour and plotted as a function of microsatellite status and tumour stage. Symbols represent individual values and the line the median. n = 10

    Journal: Cancer Immunology, Immunotherapy : CII

    Article Title: γδ T cells in human colon adenocarcinomas comprise mainly Vδ1, Vδ2, and Vδ3 cells with distinct phenotype and function

    doi: 10.1007/s00262-024-03758-7

    Figure Lengend Snippet: Vδ chain usage in tumour-infiltrating γδ T cells. Single cell suspensions were isolated from frozen tumour specimens and the CDR3 region analysed with ultra-sensitive sequencing using unique molecular identifiers. A The number of clones in the ten most frequent clonotypes from each patient. Colour coding shows the Vδ usage in the respective clonotypes. B Chord diagram showing the distribution of clones using the different Vδ chains in individual patients. C Gini-Simpson index of diversity was calculated for each tumour and plotted as a function of microsatellite status and tumour stage. Symbols represent individual values and the line the median. n = 10

    Article Snippet: Microsatellite status was determined as previously described using the microsatellite instability (MSI) Analysis System v.1.2 (ProMega) [ ].

    Techniques: Isolation, Sequencing, Clone Assay